Protein Details: Probable voltage-gated potassium channel subunit kvs-4

Protein ID

ICDB_Pro_1710

Protein Name

Probable voltage-gated potassium channel subunit kvs-4

Gene Name

kvs-4; Y48A6B.6

Organism

Caenorhabditis elegans

Length

503 amino acids

AlphaFoldDB

AF-Q9XXD1-F1-model_v4.pdb

Function

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes

Sequence

MNSAIMQGAAMATSHGIARLNRHNAQRNHFHIPTANRLFYQLQTPCTSTEEERRTVQTDDVAEIGMQRPDYQMYCGEEEISEQFVKLNVGGQRFMLRKDTIRRRGVGRLLDLINKPVADSNADAFFSSTSEFYFERPPSLFHIVYQFYLNGVIHQPSNLCPVDIIEELEYWRIIPDQYLASCCCAQQIDDDDEEVEEQDKPNLFKTLRFGEIRRCVWNIIEEPASSGKAQAFAVCSVVFVLISISGLVLGSLPELQVATKQRNNLTGEEFTEMEPMPILGYIEYVCIVWFTMEYGLKMLVSAERSKTFRQLLNIIDLLAILPFIIEMLLLIFGISTEQLRDLKGAFLVIRILRVLRVIRVLKLGRYSSGLQMFGKTLKASFRQLGMMAMVVMTGVIFFSTLVYFLEKDEPASKFHSIPAACWWCIVTMTTVGYGDLTPVTVPGKLVATGAIACGVLVLALPITIIVDNFMKVAETERPAGGNRYRTSQYPKATKSEQMILKVT

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in the cholinergic motor neuron DA9; mechanosensory neurons ALM and PLM; and the interneuron PVPL.

DOI ID

10.1126/science.282.5396.2012; 10.1002/1873-3468.12043

RefSeq

NP_001022888.1 [Q9XXD1-1]; NP_001022889.1